Fenbendazole is a member of the benzimidazole class of anthelmintic medications and has a very broad antiparasitic spectrum. In addition to being effective against the common roundworms and hookworms, it is also very useful against whipworms (Trichuriasis) and some tapeworms such as Taenia species and Giardia intestinalis.
In addition to its parasitic actions, fenbendazole has also been reported to exhibit antitumor and immunomodulatory activity in both experimental animals and human patients.5 In a model of allergic airway disease induced by ovalbumin exposure, administration of fenbendazole significantly decreased eosinophil counts in the blood and lung sections as well as reduced serum levels of ovalbumin-specific IgG1 antibody. Additionally, fenbendazole significantly decreased Th2-derived cytokines and inhibited activation of CD4+ T cells.
The use of fenbendazole in humans is considered off-label and has not been approved by regulatory agencies. However, there is growing interest and ongoing research examining its potential therapeutic applications in cancer treatment and other disorders.
Your veterinarian may recommend a compounded formulation of fenbendazole when an FDA-approved medication is not appropriate for your pet due to a condition, or if the desired dosage strength is not commercially available. Compounded medications are prepared by a licensed pharmacist on an individual basis according to the directions of your veterinarian. Compounding pharmacies can provide this service for dogs, cats, horses, ferrets and exotic species. Store fenbendazole granules at room temperature and keep away from sunlight. If your pet experiences an adverse reaction to this medication, call your veterinary office or emergency facility. fenbendazole capsules